Brain tumors and the Lynch syndrome.
Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is est...
Gespeichert in:
- 1. Verfasser:
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- Format:
- Elektronisch Buchkapitel
- Sprache:
- Englisch
- Veröffentlicht:
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IntechOpen
2011
- Zusammenfassung:
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Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003).
- Umfang:
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1 online resource (chapter 15, pages [363]-382) : illustrations; digital file(s).
text file - Anmerkungen:
- English
- Bibliografie:
- Includes bibliographical references.
- ISBN:
- 953-51-6503-8
- Schlagworte:
- Bezugswerke:
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Parallelausgabe: 953-307-646-1
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