Brain tumors and the Lynch syndrome.

Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is est...

Ausführliche Beschreibung

Gespeichert in:
1. Verfasser:
Peltomäki, Päivi
Weitere Verfasser:
Gylling, Annette (HerausgeberIn)
Format:
Elektronisch Buchkapitel
Sprache:
Englisch
Veröffentlicht:
IntechOpen 2011
Zusammenfassung:
Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003).
Umfang:
1 online resource (chapter 15, pages [363]-382) : illustrations; digital file(s).
text file
Anmerkungen:
English
Bibliografie:
Includes bibliographical references.
ISBN:
953-51-6503-8
Schlagworte:
Bezugswerke:
Links: