Histone Deacetylases Methods and Protocols /

This volume provides different methodologies for all classes of histone deacetylases, which includes detailed procedures on Class I and II histone deacetylase inhibitors, SIRT inhibitors, and bromodomain inhibitors. Histone Deacetylases: Methods and Protocols is divided into four sections: Sections...

Ausführliche Beschreibung

Gespeichert in:
1. Verfasser:
Sarkar, Sibaji.
Körperschaft:
SpringerLink (Online service)
Weitere Verfasser:
Sarkar, Sibaji (HerausgeberIn)
Format:
Elektronisch E-Book
Sprache:
Englisch
Veröffentlicht:
New York, NY : Springer New York : Imprint: Humana, 2016.
Ausgabe:
1st ed. 2016.
Zusammenfassung:
This volume provides different methodologies for all classes of histone deacetylases, which includes detailed procedures on Class I and II histone deacetylase inhibitors, SIRT inhibitors, and bromodomain inhibitors. Histone Deacetylases: Methods and Protocols is divided into four sections: Sections A and B describe methodologies used to detect the activity, function, or chromatin location of HDACs 1 through 11, with Section A discussing Class I and Section B discussing class II histone deacetylases; Section C focuses on the methodologies for cloning and characterizing the acetylation of SIRTs 1 through 7; and Section D describes methods related to histone deacetylase inhibitors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Histone Deacetylases: Methods and Protocols, is a valuable resource for investigators working on epigenetics, molecular biology, and genetics.
Umfang:
1 Online-Ressource (XII, 337 Seiten) 52 Illustrationen, 31 Illustrationen in Farbe
text file PDF
ISBN:
9781493936670
ISSN:
1940-6029 ;
DOI:
10.1007/978-1-4939-3667-0
Schlagworte:
Cytology.
Cell Biology.
Bezugswerke:
Links: