Bioisosteres in medicinal chemistry /

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism.As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development.The first part...

Ausführliche Beschreibung

Gespeichert in:
1. Verfasser:
Brown, Nathan.
Weitere Verfasser:
Brown, Nathan
Format:
Elektronisch E-Book
Sprache:
Englisch
Veröffentlicht:
Weinheim, Germany : Wiley-VCH, 2012.
Ausgabe:
1st ed.
Zusammenfassung:
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism.As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development.The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered,while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third partcovers the four
Umfang:
1 online resource (258 p.)
Anmerkungen:
Description based upon print version of record.
Anmerkungen:
English
Bibliografie:
Includes bibliographical references and index.
ISBN:
9786613688927
9783527654321
3527654321
9781280778537
1280778539
9783527654307
3527654305
9783527654338
352765433X
Schlagworte:
Bezugswerke:
Links: