Modeling and simulating cardiac electrical activity /

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser:
Krogh-Madsen, Trine, Christini, David J.
Weitere Verfasser:
Krogh-Madsen, Trine (HerausgeberIn), Christini, David J. (HerausgeberIn)
Format:
Elektronisch E-Book
Sprache:
Englisch
Veröffentlicht:
Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2020]
Zusammenfassung:
This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and also focus on specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialised researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Part of Biophysical Society-IOP series.
Umfang:
1 online resource (various pagings) : illustrations (some color).
Also available in print.
Mode of access: World Wide Web.
System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.
Anmerkungen:
"Version: 20201201"--Title page verso.
Format Details:
Mode of access: World Wide Web.
System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.
Zielpublikum:
Graduate students or other trainees entering research areas within the field of computational cardiology, biologists or other scientists with limited background knowledge on mathematical modeling.
Bibliografie:
Includes bibliographical references.
ISBN:
9780750320641
9780750320634
Schlagworte:
Heart > Electric properties > Mathematical models.
Heart > Electric properties > Computer simulation.
Heart Conduction System > physiology.
Electrocardiography.
Models, Theoretical.
Biophysics.
SCIENCE / Life Sciences / Biophysics.
Bezugswerke:
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