Mendelian randomization : methods for using genetic variants in causal estimation /

Mendelian randomization is a way of assessing causal associations from observational data, which is especially important for medical scientists and epidemiologists who want to know the true causes of diseases. Covering this emerging area of research in biostatistics and epidemiology, this book exami...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser:
Burgess, Stephen, Thompson, Simon G.
Format:
Elektronisch E-Book
Sprache:
Englisch
Veröffentlicht:
[Boca Raton] : [CRC Press], [2015]
Ausgabe:
1st edition
Zusammenfassung:
Mendelian randomization is a way of assessing causal associations from observational data, which is especially important for medical scientists and epidemiologists who want to know the true causes of diseases. Covering this emerging area of research in biostatistics and epidemiology, this book examines the use of genetic variants as instrumental variables to assess causal associations. It also discusses statistical issues with instrumental variable analysis and explores practical applications of Mendelian randomization. The methods are illustrated with a variety of detailed worked examples usi
Umfang:
1 online resource (222 p.)
text file
Anmerkungen:
Description based upon print version of record.
Anmerkungen:
English
Bibliografie:
Includes bibliographical references.
ISBN:
0-429-19022-0
1-4665-7318-X
9780429190223
Schlagworte:
Medical genetics > Statistical methods.
Bezugswerke:
Links: