Methods and Applications of Statistics in Clinical Trials, Volume 2: : Planning, Analysis, and Inferential Methods /

Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a l...

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Contributors
Chapter 1: Analysis of Over- and Underdispersed Data
Chapter 2: Analysis of Variance (ANOVA)
Chapter 3: Assessment of Health-Related Quality of Life
Chapter 4: Bandit Processes and Response-Adaptive Clinical Trials: The Art of Exploration Versus Exploitation
Chapter 5: Bayesian Dose-Finding Designs in Healthy Volunteers
Chapter 6: Bootstrap
Chapter 7: Conditional Power in Clinical Trial Monitoring
Chapter 8: Cost-Effectiveness Analysis
Chapter 9: Cox-Type Proportional Hazards Models
Chapter 10: Empirical Likelihood Methods in Clinical Experiments
Chapter 11: Frailty Models
Chapter 12: Futility Analysis
Chapter 13: Imaging Science in Medicine I: Overview
Chapter 14: Imaging Science in Medicine, II: Basics of X-Ray Imaging
Chapter 15: Imaging Science in Medicine, III: Digital (21st Century) X-Ray Imaging
Chapter 16: Intention-to-Treat Analysis
Chapter 17: Interim Analyses
Chapter 18: Interrater Reliability
Chapter 19: Intrarater Reliability
Chapter 20: Kaplan-Meier Plot
Chapter 21: Logistic Regression
Chapter 22: Metadata
Chapter 23: Microarray
Chapter 24: Multi-Armed Bandits, Gittins Index, and Its Calculation
Chapter 25: Multiple Comparisons
Chapter 26: Multiple Evaluators
Chapter 27: Noncompartmental Analysis
Chapter 28: Nonparametric ROC Analysis for Diagnostic Trials
Chapter 29: Optimal Biological Dose for Molecularly Targeted Therapies
Chapter 30: Over- and Underdispersion Models
Chapter 31: Permutation Tests in Clinical Trials
Chapter 32: Pharmacoepidemiology, Overview
Chapter 33: Population Pharmacokinetic and Pharmacodynamic Methods
Chapter 34: Proportions: Inferences and Comparisons
Chapter 35: Publication Bias
Chapter 36: Quality of Life
Chapter 37: Relative Risk Modeling
Chapter 38: Sample Size Considerations for Morbidity/Mortality Trials
Chapter 39: Sample Size for Comparing Means
Chapter 40: Sample Size for Comparing Proportions
Chapter 41: Sample Size for Comparing Time-to-Event Data
Chapter 42: Sample Size for Comparing Variabilities
Chapter 43: Screening, Models of
Chapter 44: Screening Trials
Chapter 45: Secondary Efficacy End Points
Chapter 46: Sensitivity, Specificity, and Receiver Operator Characteristic (ROC) Methods
Chapter 47: Software for Genetics/Genomics
Chapter 48: Stability Study Designs
Chapter 49: Subgroup Analysis
Chapter 50: Survival Analysis, Overview
Chapter 51: The FDA and Regulatory Issues
Chapter 52: The Kappa Index
Chapter 53: Treatment Interruption
Chapter 54: Trial Reports: Improving Reporting, Minimizing Bias, and Producing Better Evidence-Based Practice
Chapter 55: U.S. Department of Veterans Affairs Cooperative Studies Program
Chapter 56: Women's Health Initiative: Statistical Aspects and Selected Early Results
Chapter 57: World Health Organization (WHO): Global Health Situation
1. Verfasser:
Balakrishnan, N.
Format:
Elektronisch E-Book
Sprache:
Englisch
Veröffentlicht:
Wiley 2014
Ausgabe:
1st edition
Zusammenfassung:
Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features: Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planning and data management of clinical trials
Umfang:
1 online resource (960 pages)
text file
Bibliografie:
Includes bibliographical references at the end of each chapters and index.
Schlagworte:
Clinical trials > Statistical methods.
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