rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Natural Products and Drug Discovery
  name:
    name part: Avato, Pinarosa
    role:
      role term: creator
    role:
      role term: aut
  type of resource: text
  origin info:
    place:
      place term: xx#
    issuance: monographic
  physical description:
    form: remote
    extent: 1 electronic resource (392 pages)
  abstract: Natural products hold a prominent position in the current discovery and development of drugs and have diverse indications for both human and animal health. Plants, in particular, play a leading role as a source of specialized metabolites with medical effects. Other organisms, such as marine and terrestrial animals and microorganisms, produce very important drug candidate molecules. Specialized metabolites from these varied natural sources can be used directly as bioactive compounds or drug precursors. In addition, due to their broad chemical diversity, they can act as drug prototypes and/or be used as pharmacological tools for different targets. Some examples of natural metabolites that have been developed into useful medical drug are cardiotonic digoxin from Digitalis sp., antimalarial artemisinin from Artemisia annua, anti-cancer taxol from Taxus sp., or podophyllotoxin from Podophyllum peltatum, which served as a synthetic model for the anti-cancer etoposide. The study of natural products is still attracting great scientific attention and their current importance, as a valuable lead for drug discovery, is undebatable. I cordially invite authors to contribute original articles, as well as survey articles, that give the readers of Molecules **MOLECULES NEEDS TO BE ITALICIZED** updated and new perspectives on natural products in drug discovery, including but not limited to natural sources, identification and separation of bioactive phytochemicals, standardization, new biological targets, pre-clinical and clinical trials, pharmacological effects/side effects, and bioassays
  note: Open Access Unrestricted online access star
  note: eng
  subject:
    topic: Science (General)
  subject:
    topic: Biology (General)
  identifier: 9783039287468
  identifier: 9783039287475
  identifier: https://mdpi.com/books/pdfview/book/2231
  identifier: https://directory.doabooks.org/handle/20.500.12854/54359
  access condition: Open Access
  record info:
    record content source: OAPEN Foundation
    record creation date: 200609
    record change date: 20250113100402.0
    record identifier: 990367828440206441
    language of cataloging:
      language term: ger